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Misión

Mission

To improve people's health and quality of life by manufacturing highly complex injectable products that are accessible to everyone.

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Visión

Vision

To become the most reputable and reliable pharmaceutical company for our patients and partners, both nationally and internationally, providing the highest quality injectable products through sustainable growth that reduces environmental impact.

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Icono valores

Culture

Our company culture is grounded in three essential pillars: Innovation, generating advancements to improve patients' lives and contribute to the progress of the pharmaceutical industry. Achievement, always driving excellence. The Team, strengthening talent and internal collaboration to develop a great team.

History of GP Pharm

2000

Founding of GP Pharm

2001

First European approval of Somatostatin GP Pharm

2005

Construction of GP Pharm's industrial facilities

2006

First GMP approval (EMA) and first clinical batches of liposome and microsphere-based products

2007

Cephalon (now TEVA) appoints GP Pharm as exclusive manufacturer of Myocet® (Liposomal Doxorubicin)

2008

GP Pharm begins commercial activity in Spain

2009

Application for authorisation of Lutrate® Depot 3.75mg in Europe

2011

Clinical studies start for Lutrate® Depot 22.5mg. First approval of Lutrate® Depot 3.75mg in Europe

2012

Approval of Lutrate® Depot 3.75mg in Europe

2014

Application for authorisation of Lutrate® Depot 22.5mg in Europe. Approval of Lutrate® Depot 3.75mg in Canada

2015

Satisfactory GMP inspection of industrial facilities by the FDA. Approval of Lutrate® Depot 22.5mg in Europe

2016

Launch of Lutrate® Depot 22.5mg in Spain

2017

Expansion of GP Pharm's manufacturing plant

2018

Lutrate® Depot 22.5mg approved in the USA. Launch of Nictur in Europe

2019

Launch of Lutrate® Depot Quarterly in Canada

2021

Relaunch of Lutrate® Depot 3.75mg in Spain with women's health indications

2022

Launch of Lutrate® Depot 22.5mg in the U.S., Ganirelix in Spain and Europe, Teriparatide in Spain and Europe, and Icatibant in Spain

2023

Development of Teduglutide

Executive Board

Antonio Parente (Founder and President)

Dr. Antonio Parente was born in Badalona (Barcelona) and has spent most of his professional career in the pharmaceutical industry. He studied chemistry and graduated with a PhD in Organic Chemistry from the University of Barcelona (1978). His academic training includes an MBA from ESADE (1981) and a PADE - Senior Business Management Program - from IESE (2010). He is the co-author of over 40 scientific articles and patents. 

Dr. Parente began his professional career at Laboratorios Vita S.A. in charge of the Chemical and Patents Department. Since 1989, he has co-founded several companies, including Lipotec S.A., BCN Peptides S.A., Diverdrugs S.L., Lipofoods S.A., BCN Corp S.L., and Primaderm S.A., where he has held various positions such as general manager, CEO, and administrative director. In 2000, he co-founded GP Pharm, where he currently serves as Executive Chairman. 

Additionally, Dr. Parente has served as President of the Business Council of CRG (Centre for Genomic Regulation), Vice President of ASEBIO (Spanish Association of Biotechnology Companies), co-founder and President of CataloniaBio (Business Association of Biotechnology Companies of Catalonia), and Vice President of Biocat. Furthermore, he has previously acted as President of the Chemical-Pharmaceutical Section of the Official College of Chemists of Catalonia (1980-1994). Finally, Dr. Parente is an Advisory Director and/or Business Angel for more than 10 Spanish biotechnology companies.

Antonio Parente
PhD, MBA
Founder and President
Marta Parente (CEO)

Marta Parente holds a degree in Economics and Business Sciences from Pompeu Fabra University (2005) and an MBA from IESE (2010). She began her professional career in the health and cosmetics sector at the European Union Chamber of Commerce in Beijing, China (2005-2008). After completing her MBA at IESE and spending some time at Janssen Cilag S.A., Madrid, she joined Roche in 2010, working in various areas of the company in different countries (Roche Diagnostics in Sweden, Switzerland, and the USA; Roche Diabetes Care in Italy).

Finally, she joined Genentech, the American branch of Roche Pharmaceuticals, where she was responsible for Global Market Access for skin cancer products in Oncology until 2015; she then led the marketing team for the American market in Oncology; and in 2017, she became Head of Sales for the East/Mid-Atlantic zone of the USA in Oncology at Genentech.

In 2020, she joined GP Pharm as Director of New Projects and Corporate Viability, and in 2021, she assumed the role of COO of GP Pharm. In January 2022, she was appointed CEO of GP Pharm. Marta has been a member of the company's Board of Directors since 2017 and a director of BCN Peptides. In January 2024, she joined the board of CataloniaBio and in May, the board of the L’Hospitalet de Llobregat delegation of the Chamber of Commerce.

Marta Parente
MBA
Chief Executive Officer
Josep de Nadal

Josep de Nadal was born in Barcelona and holds a degree in Chemical Engineering from the Chemical Institute of Sarrià (IQS, 1968) and an MBA from ESADE (1968). He began his professional career as Brand Manager at Danone S.A. (1968-1974), was Head of Division at MasCosmetics (1974-1976), and General Manager of Laboratorios Ausonia (1976-1992).

Josep de Nadal's professional activities from 1992 to 2010 include a wide variety of managerial, executive and consulting positions in various companies, both national and international. Since 2010, Josep de Nadal has been a member of the Board of Directors of Ofistrade, Senior Advisor of Clairfield Corporate Finance, Director of Sosa Ingredients SL, and Independent Director of GP Pharm SA.

Josep de Nadal has also been a Trustee of the IQS Foundation (2006-2008) and Professor of the Master's Degree in Chemical Business Management at IQS (1982-1987). He is currently a member of the Cercle d'Economia and Vice-President of the Fundació Relleu.

Josep de Nadal
MBA
Independent Consultant
Berta Ponsati (Independent Consultant)

Dr. Berta Ponsatí was born in Barcelona and has developed her professional career in the pharmaceutical industry. She has a degree in Chemistry (1983) and a PhD in Organic Chemistry from the University of Barcelona (1985). She has extensive training and experience in peptide chemistry following her studies at the UPC (Universitat Politècnica de Catalunya) and a postdoctoral stay at the CBM (Centre for Molecular Biology) in Madrid.

She began her professional career as director of the peptide synthesis department at Lipotec S.A. (1990). In 2005, she became Managing Director of BCN Peptides S.A. From 2012 to 2021, she was also CEO of GP Pharm SA where she boosted the company's international presence, expanding its activities, such as CDMO, and consolidating its presence in the Spanish market. She is currently an Independent Director of GP Pharm SA.

In addition, Dr. Ponsatí is co-author of multiple scientific articles and patents and has co-directed several doctoral theses in the field of peptide synthesis.

Berta Ponsatí
PhD
Independent Consultant
Anna Parente, Executive Board Member

Anna Parente holds a degree in Medicine from the University of Barcelona (2004) and specialised in Haematology and Haemotherapy at the Hospital de Sant Pau, where she completed her residency. She later moved to Norway with a scholarship from Kreftforeningen (Norwegian Cancer Society) to pursue her PhD in Chronic Lymphocytic Leukaemia. Her dissertation was titled "Unravelling the Role of the Microenvironment in Chronic Lymphocytic Leukaemia: T Helper Cell Support of Cancer Cells," conducted with Dr. Ludvig Munthe's group at the University of Oslo (2018).

Subsequently, she joined the Oslo University Hospital as a consultant, specialising in Immunology, where she has worked for the past eight years. Her primary focus has been the Cellular Immunology section, where she diagnoses haematological diseases and primary immunodeficiencies, collaborating with the departments of Infectious Diseases, Paediatrics, Haematology, and Clinical Immunology.

In 2023-24, she completed an Executive Development Programme (PDD) at IESE.

Anna Parente
MD, PhD
Executive Board Member

Management Team

Cristina Mazó
Cristina Mazó
MBA
QP - Site Director
Alex de la Fuente
Alex de la Fuente
PhD
Business Development Director
Fernando Postigo
Fernando Postigo
PhD
Contract Development & Manufacturing Director
Mayte Vázquez
Mayte Vázquez
PhD
Regulatory Affairs Director
Albert Fuentes, National Sales Director
Albert Fuentes
MBA
National Sales Director
Sandra Buján
Sandra Buján
MSc
Marketing Director
Gemma Gambús
Gemma Gambús
MD, PhD, MBA
Medical Director
Marta Miró
Marta Miró
MBA
Financial Director
Xènia Sarsanedas
Xènia Sarsanedas
MA
Human Resources Director
Jaume Gabaldà
Jaume Gabaldà
MA
Head of Legal Department
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Investigación y desarrollo

Research, development and innovation

GP Pharm's research and development team is highly specialised in the microencapsulation of drugs using liposomes, lipid nanoparticles, and microspheres. Our team has extensive experience in the development and manufacture of injectable pharmaceutical products that include these technologies. The company is an expert in the microencapsulation of peptides, oligonucleotides, mRNAs, and other active ingredients.

GP Pharm's R&D laboratories have the latest technologies such as UPLC, quantitative HPTLC, HPLC, DSC, KF for water content determination, DLS and laser diffraction for particle size determination, Z potential, GPC polymer analysis, viscometry analysis, UV, FT-IR, GC, and other specific technologies for the analysis of microspheres and liposomes. 

Thanks to these analysis tools, the company can ensure fast and reliable results in the various stages of development of its pharmaceutical products, including the monitoring of scale-up processes from the laboratory to the manufacture of commercial batches. 

As a result of R+D+i efforts in the technological areas of extended-release drug systems, GP Pharm is able to develop new generations of conventional pharmaceutical products by microencapsulating the active ingredient in microspheres and liposomes. These products allow a reduction in the effective dose received by the patient, improving the efficacy and safety of the drug.

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Microesferas

Microspheres

What are microspheres and what are they used for?

Generally, pharmaceutical products must be administered several times a day over a determined period of time to achieve a constant pharmacological effect. This administration pattern can result in poor control of drug levels in the blood, leading to concentration fluctuations that may occasionally fall below the therapeutic efficacy values or above the toxicity levels of the drug in question. Especially in products with high pharmacological potency, this can lead to unwanted side effects for the patient.

Consequently, there has been increasing attention towards controlled-release drug systems to administer highly potent substances over long periods with better control over drug release compared to traditional administration systems. The main objectives of these new drug delivery systems are: reducing unwanted side effects, increasing the time between dose administrations, and achieving comprehensive control over drug release.

The primary method to achieve controlled release of the active substance is by incorporating it into a biodegradable polymeric assembly called a microcapsule. In microencapsulated drugs, the active substance is trapped within a polymeric matrix or covered and/or coated by a polymeric shell. When the product formation process results in the formation of small spherical particles, these are called microspheres.

GP Pharm's technological capabilities in the field of microspheres:

  • Obtaining microspheres using different technologies: single emulsion, double emulsion, and coacervation.
  • Proprietary and patented technology for modulating the release of the drug from the microspheres.
  • Experience in the manufacture of hydro- and fat-soluble products through the use of different types of additives on the surface of the capsule.
  • Experience in the use of biopolymers of synthetic and natural origin.
  • Manufacturing capacity of microspheres in the range of 5 to 200 μm.
  • Ability to obtain controlled-release formulas from 5-6 days to 6 months.
  • Solid and proven experience in scaling processes from the laboratory to the industrial level
  • GP Pharm develops and patents its own microsphere-based innovations.
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Liposomas

Liposomes and lipid nanoparticles

What are liposomes and what are they used for?

Liposomes are thermodynamically stable vesicular structures composed of lipid bilayers of amphiphilic lipids. Liposomes are formed spontaneously by the dispersion of phospholipids in an aqueous medium and can be described as spherical, closed, submicron-sized structures formed by one or more concentric lipid bilayers containing aqueous spaces between them. Liposomes have great potential as controlled drug delivery systems for parenteral administration thanks to their unique properties that allow the encapsulation of hydro- and fat-soluble substances. Therefore, it is an ideal release system for controlled releases with times of 1 to 4 days.

Thanks to their structure and design based on lipid components, liposomes are biocompatible, biodegradable, and non-toxic. Their application as controlled-release drug systems has been studied extensively. In addition, they are also used in the field of cosmetics, diagnostics, and in the food industry.

Especially noteworthy is the application for the release of antitumour drugs, antibacterial and antiviral treatments, and as an immunological adjuvant in vaccines. More recently, numerous studies have demonstrated their versatility when applied in gene therapy and for use as an antisense (small interfering RNA). There are currently several clinical studies with liposomal preparations and different products based on this technology can be found on the market.

GP Pharm's technological capabilities in the field of liposomes:

  • Development of in vitro release tests in different buffer solutions and in human plasma.
  • Characterisation of liposomes by cryofracture electron microscopy, cryo electron microscopy, TEM, and SEM.
  • Characterisation of drugs in liposomes by circular dichroism and X-rays.
  • DSC for the determination of transition temperatures.
  • Determination of collapse temperatures for the development of lyophilised liposome formulations.
  • Development of lyophilisation processes for liposomal formulations.
  • Solid and proven experience in scaling processes from the laboratory to the industrial level.
  • GP Pharm develops and patents its own liposome-based innovations.
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Nanoparticula lipidica

Technological platforms based on nano and microencapsulation

Nanotechnology/nanoencapsulation

With the technological advances of recent years, nanotechnology has shown enormous potential for clinical application, especially in the generation of lipid nanoparticles as vectors for drug delivery.

  • nanoemulsions
  • liposomes
  • lipid nanoparticles

New technological avenues have now been developed to obtain improved lipid nanoparticle types, such as lipid nanoparticles (LNPs), nanostructured lipid carriers such as solid lipid nanoparticles (SLNs) or lipid nanocarriers (LNCs), and lipid drug conjugates (LDCs).

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Nuevas formulaciones

New types of microencapsulated formulations

GP Pharm's high experience in the development and production of final products (lyophilised, solutions, microspheres, and liposomes) containing active principles such as peptides, DNA, RNA, HPAPIs, cytotoxics, among others, opens up enormous potential for the new development of improved formulations with greater stability, more suitable for patients, and with a more controlled drug release.

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Instalaciones industriales

Industrial facilities

GP Pharm's industrial facilities are located in an area of 35,000 square metres in Sant Quintí de Mediona (approximately 50 km west of Barcelona). Inaugurated in 2005, the project was designed considering a possible growth of the facilities in parallel to that of the company. In fact, in 2017 part of the facilities were expanded and renovated to double the manufacturing capacity and adapt to the growing demand. Currently, they occupy 3,651m² and the industry has 8 buildings, of which 3 are exclusively dedicated to the manufacture of pharmaceutical products. The rest is used for offices, laboratories, logistics, and supplies. Our R+D and quality control laboratories are located in the same industrial area for greater control in the development and validation of the analytical methods used in production control. The co-location of the R+D and production teams allows GP Pharm to establish an optimal collaboration to ensure a smooth transition from laboratory development to scale-up to industrial processes.

In 2024, the execution of a new project to expand the facilities has begun, in order to create new production lines equipped with the most innovative technology, which will reach completion in 2026 with an operational occupancy of 8,000 m².

Our industrial facilities offer a high production capacity and advanced technological systems that, together with a highly trained and committed technical team, allow us to develop and manufacture safe and efficient pharmaceutical products. The factory is specially prepared for the production and packaging of injectable products including:

  • Controlled-release drug systems: microspheres and liposomes.
  • High potency drugs (peptides, oligonucleotides, hormones, etc.).
  • Cytotoxic agents for the treatment of different types of cancer.
  • Intermediate-potency drugs.
  • Non-active buffers and reconstitution solutions.

Finished dosage forms of non-active buffers and reconstitution solutions

Drug Delivery Systems: microspheres and liposomes

Finished dosage forms of high potency drug substances (peptides, oligonucleotides, hormones, etc.)

Finished dosage forms of cytotoxic active ingredients with indications for the treatment of cancer

Finished dosage forms of drug substances with an intermediate potency

Areas of expertise

Medical department

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Departamento médico

The medical department designs, conducts, and coordinates the complete clinical development of our pharmaceutical products. The extensive know-how of our team in all areas of this process guarantees the correct development from the preclinical phase to phase IV studies, ensuring quality control.

They are also specialised in medical affairs, being a pillar for the product strategy and providing high value in scientific communication with all stakeholders, including national and international regulatory agencies.

Our team has extensive experience—academic profiles with master's degrees and doctorates—in the validation, design, and conduct of clinical studies, generation of scientific evidence, medical positioning of our products, communication, and scientific training. These functions mean that it works in constant collaboration with the different departments of the company, providing support, among others, to pharmacovigilance, market access, and regulatory aspects.

Our cornerstone is to ensure the health and well-being of patients from the initial phases of research to clinical practice.

Intellectual Property

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Propiedad intelectual

GP Pharm develops innovative products and technologies in the field of the pharmaceutical industry. In order to protect the significant value of the company's intellectual property generated in its laboratories, the company has created a comprehensive international patent portfolio.

GP Pharm holds more than 100 patents and patent applications in more than 50 countries, protecting key products and technologies including, but not limited to, controlled drug release system formulations.

Supply chain

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Cadena de suministro

The supply chain of GP Pharm's pharmaceutical products is perfectly integrated: reception, identification, storage, order preparation, documentation, shipment, and distribution are perfectly monitored to have perfect traceability of the shipment of the product to the customer and ensure the quality and storage of it under the authorised conditions.

The company has extensive experience in shipping temperature-controlled products anywhere in the world, including ambient temperature (<25ºC), cold (between 2 and 8ºC), and/or below zero (-20ºC). We work with the best suppliers of active and passive temperature control systems, carefully choosing the most suitable one according to the shipping system to guarantee the quality of the final product at destination.

The company assumes responsibility for the preparation of export documentation according to the different regulations of each country to facilitate the import process for the customer and expedite shipping.

Customer Service

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Servicio al cliente

Our customer service, both nationally and internationally, fully monitors all sales processes, from the moment of receipt of the order to its delivery, to guarantee the best service and satisfaction to our customers. In this regard, we are committed to providing an exceptional level of service through our attention to detail and a deep understanding of the needs of each of our clients.

Regulatory Affairs

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Regulatory Affairs

GP Pharm's regulatory affairs team has extensive experience in registration procedures worldwide, especially at the European level (NP, DCP, CP, MRP) and in the USA. It also has extensive experience in supporting registration procedures in other territories such as Canada, Australia, ASEAN, APAC, MENA, LATAM, among others.

GP Pharm's core capabilities include:

  • Preparation of new dossiers in e-CTD format.
  • Audits of registration dossiers and DMFs.
  • Processing of authorisation processes and updating of registration dossiers in different regions.
  • Support to clients in regulatory procedures in different territories.

Pharmacovigilance Department

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Farmacovigilancia

The pharmacovigilance team works to ensure the safety and efficacy of our medicines during development, marketing, and the entire life cycle of the product, monitoring the adverse effects linked to our medicines and complying with the health obligations associated with pharmacovigilance.